Quantitative Photoacoustic Imaging of Regional Kidney Changes in a Mouse Model of Ischemia–Reperfusion Injury

Moothanchery, Mohesh (2026) Quantitative Photoacoustic Imaging of Regional Kidney Changes in a Mouse Model of Ischemia–Reperfusion Injury. [Data Collection]

Description

This study investigated the utility of multispectral optoacoustic tomography (MSOT), a photoacoustic imaging (PAI) technique, for longitudinal monitoring of r-IRI in a mouse model. PAI enabled real-time assessment of cortical oxygen saturation (mSO₂), while cortical renal filtration (FT) and excretion (ET) coefficients were evaluated using a near-infrared contrast agent. Nine mice with unilateral r-IRI were imaged at baseline, day 1, and day 15 to assess acute injury and recovery.

Keywords:	Photoacoustic Imaging, Multispectral Optoacoustic Tomography, Ischemia-reperfusion, Oxygen saturation, Dynamic Contrast Enhanced PAI
Date Deposited:	04 Jun 2026 14:16
Last Modified:	04 Jun 2026 14:16
DOI:	10.17638/datacat.liverpool.ac.uk/3089
URI:	https://datacat.liverpool.ac.uk/id/eprint/3089
Additional details Additional details Creators: Moothanchery, Mohesh Corporate creators: The authors acknowledge the use of and expert support by the Centre for Preclinical Imaging (CPI) and the Biomedical Sciences Unit (BSU), provided by the Liverpool Shared Research Facilities, Faculty of Health and Life Sciences, University of Liverpool. T Collection period: From To 28 October 2021 4 May 2022 Date: 4 June 2026 Date type: Publication Resource language: English Publisher: University of Liverpool Contact email address: moheshm@liverpool.ac.uk Last Modified: 04 Jun 2026 14:16

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