Notes for the datacat dataset for 'Sidechain modulation of responsive metal-organic framework pore chirality for enhanced enantioseparation'. This dataset contains raw experimental data. All files are text files which are delimited by tabs, spaces or commas and therefore can be read into programmes such as Microsoft Excel or Origin or viewed as text files in any text editor. The relevant variables and units, where applicable, are provided as column headings for each data set. The experimental source of data is explained in the supplementary information of the paper. Experimental Data: The file "PXRD_ZnValPyr.zip" contains Powder X-ray diffraction (PXRD) data collected for the series of ZnValPyr structures discussed in the publication The file "1H NMR_ZnValPyr_DMF.csv" contains the nuclear magnetic resonance data for the ZnValPyr material. The file "CO2 adsorption_ZnValPyr.csv" contains the CO2 adsorption desorption data for the ZnValPyr material The file "HPLC_ZnValPyr.zip" contains High Performance Liquid Chromatography data for the series of separations discussed in the paper.