Genetic mapping and characterisation of triclabendazole resistance in the liver fluke, Fasciola hepatica

The liver fluke Faciola hepatica is a parasite of global significance to the livestock industry. Triclabendazole is
the treatment of choice given its activity against juvenile and adult stages of the parasite. However, resistance 
has developed to this drug. We performed genetic mapping to localise the region under selection followed by analysis
of field isolates to further validate and characterise the molecular basis of triclabendazole resistance.

Full details of the methods and locus positions are available in the publication linked to this data set.

1. LGC Genotyping
Raw data received from LGC Genomics giving a genotype for each individual Fasciola hepatica parasite at each locus
Columns = each locus genotyped
Rows = each parasite genotyped
? = genotyping unsuccessful

*DNA sample IDs as follows:	
AS2_*_r	= Parental FhLivR1
AS2_*_s	= Parental FhLivS1
41_*; 42_*; 43_*; 44_* = F1 cross untreated animals
45_*; 46_* = F1 cross treated animals
1876_*; 1893_*; 1895_*; 1903_*; 1905_* = F2 cross Experiment 1 untreated animals
1880_*; 1888_*; 1891_*; 1899_*; 1901_* = F2 cross Experiment 1 treated animals
115_*; 116_*; 119_*; 120_*; 124_* = F2 cross Experiment 2 untreated animals
111_*; 112_*; 113_*; 114_* = F2 cross Experiment 2 treated animals

** Locus IDs as follows:
scaffoldNumber_locusNumber
shading indicates monomorphic locus